Principles of VariO

VariO can be used for description of variations

• of whatever type (natural/engineered)
• of whatever size
• in whatever organism
• of any mechanism
• with experimentally verified or predicted effect(s)

VariO

• does not describe actual variation on nucleotide/protein level
• does not contain any clinical information

VariO is position specific. It can be used to explain whatever size of variation ranging from single nucleotide to entire genome.

VariO explains the change caused by the variation, not the normal/wild type property, function etc.

VariO reuses of terms and definitions from existing ontologies including